Principal Investigator
Ralph Pantophlet, PhD
Professor, Faculty of Health Sciences
Associate Member, Department of Molecular Biology and Biochemistry
Michael Smith Foundation for Health Research Scholar (2012-2020)
Canadian Institutes of Health Research New Investigator (2009-2015)
Office: Blusson Hall, Room 11712
Phone: (778) 782-8648 | Fax: (778) 782-5927 | Email: rpantophlet@sfu.ca
Profile: FHS faculty profile | Feature: Canadian Association for HIV Research (CAHR)
Education
- B.Sc., Polytechnic Faculty, Hogeschool Rotterdam, The Netherlands
- Ph.D., University of Leiden, The Netherlands/Research Center Borstel, Germany
Biography
Dr. Pantophlet is a tenured Professor in the Faculty of Health Sciences and an Associate Faculty member of the Department of Molecular Biology and Biochemistry. He joined the Faculty of Health Sciences in 2008 and is currently the head of the Laboratory of Infectious Diseases Immunology, the Flow Cytometry Lab, and the Biocontainment for Infectious Organisms level 3 (BIO3) Lab. He received his B.Sc. in medical microbiology from the Hogeschool Rotterdam & Omstreken in 1995 and his Ph.D. from the University of Leiden in 1999 for his research on the immunochemical properties of Acinetobacter lipopolysaccharides. He then did postdoctoral research on anti-HIV antibodies and vaccine design at The Scripps Research Institute under the mentorship of Dr. Dennis Burton, before returning to the Research Center Borstel for a brief period and rejoining the Burton laboratory as a senior postdoctoral fellow to focus on HIV-1 vaccine design in 2003.
Current Team
Research Assistant/Tech 3 (2023-present)
Research Assistant/Tech 2 (2020-2023)
Research Assistant (2019-2020)
kwn5@sfu.ca
Research
My past research experience has solidified my passion for antiviral research. As a member of the Pantophlet Lab, I have had the opportunity to develop a wide range of laboratory skills, including flow cytometry, protein purification, and mammalian tissue culture. These skills have allowed me to contribute to ongoing research projects and make meaningful contributions to the lab’s efforts to design more effective vaccines against viruses such as HIV and influenza.
In addition to my primary research responsibilities, I play an important role in mentoring and supporting other members of the lab. As a research-experienced lab member, I am able to guide and assist less-experienced lab members with their research work, providing them with the knowledge and support they need to succeed. I take great pride in helping others and fostering a positive and collaborative environment within the lab.
Other Interests
I am an easy-going and cheerful individual with great love for nature and travelling. I enjoy hiking, kayaking and skiing when on vacation. In particular, I love spending time with my family and friends meandering along a nice easy trail where relaxed and delightful conversations can take place.
Research Assistant/Tech 1 (2024-present)
Lab Assistant (2023-2024)
Undergraduate research intern (2022)
oxing@sfu.ca
Research
I graduated from Simon Fraser University in 2023 with a Bachelor’s degree majoring in Biological Sciences with a focus on cells, molecules, and physiology and a minor in Health Sciences specializing in life science. I have a deep interest in the field of immunology, and I am particularly eager to delve into vaccine research. I am incredibly grateful for the opportunity to be a member of the Pantophlet Lab, where I have been able to contribute to ongoing research on understanding mutational pathways that lead to the development of broadly reactive neutralizing antibodies targeting the antigenically conserved hemagglutinin stem of flu viruses. This research aims to improve the effectiveness of current flu vaccines and develop new, more effective vaccines in the future. I am excited to continue learning and growing in this field as I pursue further education and professional opportunities.
Other Interests
I like watching movies and reading fictions in my free time. I love nature and often go on walks along the beach or in the woods. I have also been playing the flute for 14 years and enjoy playing or listening to music to relax. Additionally, I love spending time with my family and my dog, as well as cooking and bird-watching.
Graduate student (2024-present)
BSc Honours (2024)
angela_omrani@sfu.ca
Research
I am a Beedie Luminaries Scholar and a Master’s student at SFU, specializing in molecular biology and biochemistry. My educational journey has been unique, fostering resilience and adaptability from many past challenges. Having completed my Honour’s project in the Pantophlet Lab, I am eager to continue contributing to research using a human-antibody transgenic mouse model on possible avenues to induce broadly neutralizing antibodies (bnAbs) with a germline-targeting HIV-1 vaccine candidate. I am passionate about research and aspire to attend medical school after completing my Master’s.
Other Interests
In my spare time, I enjoy learning and developing new skills. I am passionate about swimming, hiking and reading, and I also love a good TV show or movie marathon.
Postgraduate research intern (2024-present)
sayma_hussain@sfu.ca
Research
I am excited to contribute to the Pantophlet Lab, where we explore antibody responses to viruses to design better vaccines. My project focuses on refining antibody display on yeast to improve antibody expression and antigen binding. This work not only deepens our understanding of immune responses but also advances the development of innovative approaches for antibody discovery against viruses that are significant to global health.
Other Interests
You will often find me chilling with friends, watching movies, and listening to music in my downtime. I also enjoy capturing the beauty of nature and architecture through my camera lens. Badminton is another passion – I am always up for a game!
Research Associate (2024-present)
Postdoc (McGill University, 2021-2024)
anejatie@sfu.ca
Research
I am a dedicated researcher with a PhD in Chemistry, passionate about developing diagnostics and therapies for human diseases and cancer. I have over ten years of experience in organic synthesis, enzymology, chemical biology, glycobiology, molecular biology, and translational medicine. I have developed assays, designed and synthesized immunogens, screened antibody-secreting hybridomas, and tested drugs in cancer mouse models. I have also produced and purified antibodies and antigens and conducted high-throughput screenings of bioactive molecules. My work has resulted in publications, patents, and presentations, reflecting my commitment to advancing science. At the Pantophlet Lab, I am excited to contribute to ongoing research and help develop innovative antibody therapeutics for the PROGENITER project.
Other Interests
I love to travel and explore nature with my family. When I have free time, I love to discover BC’s craft beer culture and often brew my concoctions from time to time.
Undergraduate research intern (2024-present)
rya49@sfu.ca
Research
I am a 4th-year BSc student majoring in Molecular Biology and Biochemistry. I am incredibly interested in drug development, particularly creating treatments that might boost immunity or treat infectious diseases like HIV and HBV. In the Pantophlet Lab, I assist more senior researchers with DNA plasmid preparation, antibody cloning and purification. It is my honour to be able to participate in and contribute to research done in the Pantophlet lab.
Other Interests
Outside of research and study, I enjoy working on solo or group projects with friends, often involving hardware or software experimentation. I also spend time growing crops and, when I’m not working on projects, I like to go hiking, either alone or with friends. While I used to consider going to the gym a hobby, it’s now a daily habit that’s become part of my routine.
Undergraduate research intern (2024-present)
annabella_wang@sfu.ca
Research
I am a fourth-year student pursuing a Bachelor’s degree in Biological Sciences at Simon Fraser University. My experience with allergen immunotherapy ignited my fascination with the immune system and sparked a deep interest in immunology and vaccine development. The power of the immune system offers unlimited research potential. I am eager to expand my knowledge beyond the classroom and excited about the opportunity to contribute to real-world applications in the Pantophlet lab. I hope to pursue an Honours research project in the future.
Other Interests
I enjoy watching documentaries and TV series, as well as reading fiction and popular science books. Travelling is one of my favourite ways to enjoy vacations, as it helps me recharge while exploring diverse landscapes. I also love spending time with friends, whether we are relaxing on a sunny beach, hunting for great food, or cooking at home together.
Postgraduate research intern (2024-present)
seljazam@sfu.ca
Research
I recently graduated with a Bachelor’s in Molecular Biology and Biochemistry from SFU, where I developed a strong interest in immunology. A cancer research course further sparked my fascination with harnessing the immune system to develop targeted therapies, such as drugs that attack cancer cells. I plan to pursue this interest by moving into pharmacy, where I can contribute to drug development research focusing on immune-based therapies. In the meantime, I am eager to gain hands-on experience and acquire new skills by volunteering in the Pantophlet Lab.
Other Interests
In my free time, I enjoy watching hockey, exploring new music, taking relaxing walks, and spending quality time with friends.
Past Lab Members
Andrii Yevchuk, Postgraduate Student (Freie Universität Berlin) | MITACS Globalink Research Intern (2024) |
Kiana Roshanzamir, Undergraduate Student | Undergraduate research intern (2024) |
Nicole Goussiatiner, Undergraduate Student | Undergraduate research intern (2024) |
Sue Kang, Undergraduate Student | Undergraduate research intern (2024) |
Jason (Myung Ho) Eom, Undergraduate Student (Simon Fraser University) | HSCI 489 Undergraduate student researcher (2024) |
Ines Ciccateri, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2024) |
Ernest Hoptioncann, Undergraduate Student (Simon Fraser University) | HSCI 489 Undergraduate student researcher (2024) |
Phuong Nghi (Krystal) Bui, BSc | Graduate research intern (2023-2024) |
Sadra Afshar Moghaddam, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2023-2024) |
Angela Wiehahn, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2023-2024) |
Muskanpreet Jammu, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2023) |
Richard Alex, Undergraduate Student (Simon Fraser University) | Co-op Lab Assistant (2023) |
Harleen Buttar, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2023) |
Irene Cheng, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2023) |
Bennett Lee, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2023) |
Nadia Ahmed, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2023) |
Hana Moosaakbari, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2022-2023) |
Nathaniel Cortese, Undergraduate Student (Simon Fraser University) |
Undergraduate research intern (2023)
BISC 499 Undergraduate student researcher (2022) BISC 498 Undergraduate student researcher (2022) |
Tina Nguyen, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2022) |
Brenna Lee, Undergraduate Student (Simon Fraser University) |
Undergraduate research intern (2022)
Co-op Lab Assistant (2022) |
Mackenzie Sturn, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2022) |
Abhimanyu Minhas, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2022) |
Sarah Wong, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2022) |
Isabel Laprise, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2022) |
Mariam Hakimi, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2022) |
Angelica Macapagal, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2022) |
Manjot Sidhu, Undergraduate Student (Simon Fraser University) | BISC 498 Undergraduate student researcher (2022) |
Shannen Arviola | Undergraduate research intern (2021) |
David Savage | BISC 499 Undergraduate student researcher (2021) |
Mehrad Hassan-Dokht-Firouz | BISC 498 Undergraduate student researcher (2021) |
Simran Basra | Co-op Lab Assistant (2021) |
Li Yi Lim, Undergraduate Student (Simon Fraser University) |
Undergraduate research intern (2021-2022)
VPR Undergraduate Student Research Award (USRA) Recipient (2021) |
Diana Yang | FHS Dean's Undergraduate Student Research Award (USRA) Recipient (2020) |
Hajar Chihab, PhD | Postdoctoral Fellow (2020-2022) |
Simon Wang |
Molecular Biology and Biochemistry Honours student (2020)
Undergraduate Research Intern (2020) |
Yiqiu Yang |
FHS Dean's Undergraduate Student Research Award (USRA) Recipient (2020)
Undergraduate Research Intern (2019-2020) |
Edarlin Royce Bigornia, BSc | Undergraduate Researcher/Intern (2019-2020) |
Alejandra Jahns | Undergraduate Research Intern (2019) |
Quiana Ang, BSc Hons (Simon Fraser University) |
Graduate Student (2020-2022)
VPR Undergraduate Student Research Award (USRA) Recipient (2020) Undergraduate research intern (2019-2020) |
Sophie Fu, MSc | Research Assistant/Intern (2019-2020) |
Tess Kirilenko, BSc |
Undergraduate Researcher (2019)
GlycoNet Summer Award Recipient (2019) |
Asa Lau | Undergraduate Research Intern (2019) |
Jean-François Bruxelle, PhD | Postdoctoral Fellow (2018-2021) |
Natallia Varankovich, PhD | Senior Research Assistant (2019) |
Nikki Atanasova, MSc | Research Assistant (2018) |
Dahn Hahm, MSc | Research Assistant (2018) |
Gurshaan Sidhu | Undergraduate Research Intern (external) (2018) |
Vanesa Tomas Bosch, MSc | Senior Research Assistant (2018) |
Heather Galley, BSc (Hons) | Research Assistant (2018) |
Helen Do | Undergraduate Research Intern (2018) |
Lea Sanchez Milde, BSc | Lab Assistant (part-time) (2018) |
Michelle Chan YeeTeng | Undergraduate Research Intern (2018) |
Quratulain Qureshi | Undergraduate Research Intern (2018) |
Naiomi Lu, BSc |
Undergraduate Research Intern (2017)
VPR Undergraduate Student Research Award (USRA) Recipient (2017) Lab Assistant (2017-2018) |
Sreedevi Kesavan | Undergraduate Research Intern (2017) |
Daniella Bavaro | Undergraduate Research Intern (2017) |
Saru Sandhu | Undergraduate Research Intern (2017) |
Shianne Bains | Undergraduate Research Intern (2017) |
Alekhya Josyula, BSc | MSc student (2014-2017) |
Vivian Qian Liu, PhD | Postdoctoral Fellow (2016) |
Iva Demirova |
Grade 11 Pre-International Baccalaureate (IB) Research Intern (2015-2016)
National Sanofi Biogenius Award Student (2016) |
Nina Maglanoc | Undergraduate Research Intern (2015-2016) |
Ruth Wijaya |
Undergraduate Research Intern (2014-2016)
Undergraduate Research Award (USRA) Student (2015) |
Jessica Parker | Undergraduate Research Intern (2015) |
Alexandra Vela | Research Intern (2015) |
Caitlin Rempel |
Undergraduate Research Intern (2013-2014)
Research Assistant & Acting Lab Manager (2014) |
Timothy Crowe | MSc Student (2013-2014) |
Megan Curpen | Research Intern (2013-2014) |
Natalia Savasteeva | Visiting Student (Concordia U) Research Intern (2014) |
Simrita Sandhu | Research Intern (2014) |
Barinder Sangha | Honors Student (2014) |
Natalie Kinloch | Research Intern (2014) |
Dennis Chau |
Research Assistant & Acting Lab Manager (2013-2014)
Research Intern (2010-2011; 2012-2013) |
Angela Trinh | Research Intern (2013) |
Sophia Tsai | Research Intern (2013) |
Kate Auyeung, BSc |
Senior Research Assistant (2009-2013)
Lab Manager (2011-2013) |
Allan Linde | Research Intern (2012) |
Jessica Sidhu | Research Intern (2012) |
Sunny Tang | Research Intern (2011-2012) |
Savrina Manhas, BSc | MSc Student (2010-2012) |
Fatima Ahmed, BSc | MSc Student (2010-2012) |
Irina Vicol | Honors Student (2012) |
Maxim Parfyonov | Research Intern (2012) |
Lauretta Yu | Research Intern (2011) |
Lisa Kieneker | Honors Student (2011) |
Ben Chan | Undergraduate Research Assistant (2011) |
Matt Michaleski |
Honors Student (2010)
Lab Assistant (2010-2011) |
Brenda Clark, MSc |
Senior Research Assistant (2009-2011)
Lab Manager (2009-2011) |
Basim Nehal | Research Intern (2011) |
Jose-Tam Huang | Research Intern (2010-2011) |
James Kwon | Research Intern (2010-2011) |
Sima Gerami | Research Intern (2010) |
Abby Lin | Research Intern (2010) |