Principal Investigator
Ralph Pantophlet, PhD
Professor, Faculty of Health Sciences
Associate Member, Department of Molecular Biology and Biochemistry
Michael Smith Foundation for Health Research Scholar (2012-2020)
Canadian Institutes of Health Research New Investigator (2009-2015)
Office: Blusson Hall, Room 11712
Phone: (778) 782-8648 | Fax: (778) 782-5927 | Email: rpantophlet@sfu.ca
Profile: FHS faculty profile | Feature: Canadian Association for HIV Research (CAHR)
Education
- B.Sc., Polytechnic Faculty, Hogeschool Rotterdam, The Netherlands
- Ph.D., University of Leiden, The Netherlands/Research Center Borstel, Germany
Biography
Dr. Pantophlet is a tenured Professor in the Faculty of Health Sciences and an Associate Faculty member of the Department of Molecular Biology and Biochemistry. He joined the Faculty of Health Sciences in 2008 and is currently the head of the Laboratory of Infectious Diseases Immunology, the Flow Cytometry Lab, and the Biocontainment for Infectious Organisms level 3 (BIO3) Lab. He received his B.Sc. in medical microbiology from the Hogeschool Rotterdam & Omstreken in 1995 and his Ph.D. from the University of Leiden in 1999 for his research on the immunochemical properties of Acinetobacter lipopolysaccharides. He then did postdoctoral research on anti-HIV antibodies and vaccine design at The Scripps Research Institute under the mentorship of Dr. Dennis Burton, before returning to the Research Center Borstel for a brief period and rejoining the Burton laboratory as a senior postdoctoral fellow to focus on HIV-1 vaccine design in 2003.
Current Team
Research Assistant/Tech 3 (2023-present)
Research Assistant/Tech 2 (2020-2023)
Research Assistant (2019-2020)
kwn5@sfu.ca
Research
My past research experience has solidified my passion for antiviral research. As a member of the Pantophlet Lab, I have had the opportunity to develop a wide range of laboratory skills, including flow cytometry, protein purification, and mammalian tissue culture. These skills have allowed me to contribute to ongoing research projects and make meaningful contributions to the lab’s efforts to design more effective vaccines against viruses such as HIV and influenza.
In addition to my primary research responsibilities, I play an important role in mentoring and supporting other members of the lab. As a research-experienced lab member, I am able to guide and assist less-experienced lab members with their research work, providing them with the knowledge and support they need to succeed. I take great pride in helping others and fostering a positive and collaborative environment within the lab.
Other Interests
I am an easy-going and cheerful individual with great love for nature and travelling. I enjoy hiking, kayaking and skiing when on vacation. In particular, I love spending time with my family and friends meandering along a nice easy trail where relaxed and delightful conversations can take place.
Research Assistant/Tech 1 (2024-present)
Lab Assistant (2023-2024)
Undergraduate research intern (2022)
oxing@sfu.ca
Research
I graduated from Simon Fraser University in 2023 with a Bachelor’s degree majoring in Biological Sciences with a focus on cells, molecules, and physiology and a minor in Health Sciences specializing in life science. I have a deep interest in the field of immunology, and I am particularly eager to delve into vaccine research. I am incredibly grateful for the opportunity to be a member of the Pantophlet Lab, where I have been able to contribute to ongoing research on understanding mutational pathways that lead to the development of broadly reactive neutralizing antibodies targeting the antigenically conserved hemagglutinin stem of flu viruses. This research aims to improve the effectiveness of current flu vaccines and develop new, more effective vaccines in the future. I am excited to continue learning and growing in this field as I pursue further education and professional opportunities.
Other Interests
I like watching movies and reading fictions in my free time. I love nature and often go on walks along the beach or in the woods. I have also been playing the flute for 14 years and enjoy playing or listening to music to relax. Additionally, I love spending time with my family and my dog, as well as cooking and bird-watching.
Undergraduate research intern (2023-present)
sadra_afshar_moghaddam@sfu.ca
Research
I am a third-year Health Sciences major in the BSc Life Sciences concentration and am fascinated with biology-centric courses, including genetics, pathophysiology, and biochemistry. My career ambition is to secure a position in the medical field and positively impact people’s lives. I am thrilled by the opportunity to volunteer in the Pantophlet Lab and provide general support to active projects.
Other Interests
I love playing soccer in my free time and enjoy listening to 50s and 60s Blues music, especially from James Booker. Traveling and exploring new places is a life goal of mine; I enjoy learning about different cultures and cuisines and gaining perspective on how people live their lives around the world.
Graduate student (2024-present)
BSc Honours (2024)
angela_omrani@sfu.ca
Research
I am a Beedie Luminaries Scholar and a Master’s student at SFU, specializing in molecular biology and biochemistry. My educational journey has been unique, fostering resilience and adaptability from many past challenges. Having completed my Honour’s project in the Pantophlet Lab, I am eager to continue contributing to research using a human-antibody transgenic mouse model on possible avenues to induce broadly neutralizing antibodies (bnAbs) with a germline-targeting HIV-1 vaccine candidate. I am passionate about research and aspire to attend medical school after completing my Master’s.
Other Interests
In my spare time, I enjoy learning and developing new skills. I am passionate about swimming, hiking and reading, and I also love a good TV show or movie marathon.
Undergraduate research intern (2024-present)
ines_ciccateri@sfu.ca
Research
I’m a second-year Health Sciences student excited to volunteer in the Pantophlet Lab to provide general lab support, gain hands-on experience and learn more about vaccine immunology. I hope the knowledge and skills I gain here will aid my understanding and learning of health sciences as I continue my degree.
Other Interests
Outside of academics, I am passionate about physical activity and getting outdoors! I currently row with SFU’s Rowing Club and in my spare time I like to rock climb, hike, and read.
Postgraduate research intern (2024-present)
sayma_hussain@sfu.ca
Research
I am excited to contribute to the Pantophlet Lab, where we explore antibody responses to viruses to design better vaccines. My project focuses on refining antibody display on yeast to improve antibody expression and antigen binding. This work not only deepens our understanding of immune responses but also advances the development of innovative approaches for antibody discovery against viruses that are significant to global health.
Other Interests
You will often find me chilling with friends, watching movies, and listening to music in my downtime. I also enjoy capturing the beauty of nature and architecture through my camera lens. Badminton is another passion – I am always up for a game!
Undergraduate research intern (2024-present)
sue_kang@sfu.ca
Research
As a 4th-year Biomedical Physiology student, I have substantial hands-on laboratory experience. My co-op placements included roles as a Microbiology Laboratory Technician at Bureau Veritas and as a BioBank Research Assistant at BC Children’s Hospital. I am passionate about research and look forward to contributing to the Pantophlet Lab. I am eager to apply my skills, learn new techniques, and gain further knowledge. I am excited about the potential to grow and actively participate in cutting-edge research.
Other Interests
In my spare time, I enjoy staying active and being outdoors. I love running, playing sports and going on hikes. I also enjoy spending time with friends, travelling, and trying new food.
Undergraduate research intern (2024-present)
kroshanz@student.ubc.ca
Research
I have just finished my first year at the University of British Columbia, where I hope to major in biochemistry. My enthusiasm for science has driven me to seek volunteer opportunities, and I am particularly excited about the prospect of contributing to the Pantophlet lab. I am very excited to experience being in the lab, learn more about the research, and explore my interests in science further.
Other Interests
I enjoy journalling in my notebooks in the morning and cooking delicious meals. I also cherish spending time with family and friends, watching movies and dancing to pop music.
Past Lab Members
Andrii Yevchuk, Postgraduate Student (Freie Universität Berlin) | MITACS Globalink Research Intern (2024) |
Nicole Goussiatiner, Undergraduate Student | Undergraduate research intern (2024) |
Jason (Myung Ho) Eom, Undergraduate Student (Simon Fraser University) | HSCI 489 Undergraduate student researcher (2024) |
Ernest Hoptioncann, Undergraduate Student (Simon Fraser University) | HSCI 489 Undergraduate student researcher (2024) |
Phuong Nghi (Krystal) Bui, BSc | Graduate research intern (2023-2024) |
Angela Wiehahn, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2023-2024) |
Muskanpreet Jammu, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2023) |
Richard Alex, Undergraduate Student (Simon Fraser University) | Co-op Lab Assistant (2023) |
Harleen Buttar, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2023) |
Irene Cheng, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2023) |
Bennett Lee, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2023) |
Nadia Ahmed, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2023) |
Hana Moosaakbari, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2022-2023) |
Nathaniel Cortese, Undergraduate Student (Simon Fraser University) |
Undergraduate research intern (2023)
BISC 499 Undergraduate student researcher (2022) BISC 498 Undergraduate student researcher (2022) |
Tina Nguyen, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2022) |
Brenna Lee, Undergraduate Student (Simon Fraser University) |
Undergraduate research intern (2022)
Co-op Lab Assistant (2022) |
Mackenzie Sturn, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2022) |
Abhimanyu Minhas, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2022) |
Sarah Wong, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2022) |
Isabel Laprise, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2022) |
Mariam Hakimi, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2022) |
Angelica Macapagal, Undergraduate Student (Simon Fraser University) | Undergraduate research intern (2022) |
Manjot Sidhu, Undergraduate Student (Simon Fraser University) | BISC 498 Undergraduate student researcher (2022) |
Shannen Arviola | Undergraduate research intern (2021) |
David Savage | BISC 499 Undergraduate student researcher (2021) |
Mehrad Hassan-Dokht-Firouz | BISC 498 Undergraduate student researcher (2021) |
Simran Basra | Co-op Lab Assistant (2021) |
Li Yi Lim, Undergraduate Student (Simon Fraser University) |
Undergraduate research intern (2021-2022)
VPR Undergraduate Student Research Award (USRA) Recipient (2021) |
Diana Yang | FHS Dean's Undergraduate Student Research Award (USRA) Recipient (2020) |
Hajar Chihab, PhD | Postdoctoral Fellow (2020-2022) |
Simon Wang |
Molecular Biology and Biochemistry Honours student (2020)
Undergraduate Research Intern (2020) |
Yiqiu Yang |
FHS Dean's Undergraduate Student Research Award (USRA) Recipient (2020)
Undergraduate Research Intern (2019-2020) |
Edarlin Royce Bigornia, BSc | Undergraduate Researcher/Intern (2019-2020) |
Alejandra Jahns | Undergraduate Research Intern (2019) |
Quiana Ang, BSc Hons (Simon Fraser University) |
Graduate Student (2020-2022)
VPR Undergraduate Student Research Award (USRA) Recipient (2020) Undergraduate research intern (2019-2020) |
Sophie Fu, MSc | Research Assistant/Intern (2019-2020) |
Tess Kirilenko, BSc |
Undergraduate Researcher (2019)
GlycoNet Summer Award Recipient (2019) |
Asa Lau | Undergraduate Research Intern (2019) |
Jean-François Bruxelle, PhD | Postdoctoral Fellow (2018-2021) |
Natallia Varankovich, PhD | Senior Research Assistant (2019) |
Nikki Atanasova, MSc | Research Assistant (2018) |
Dahn Hahm, MSc | Research Assistant (2018) |
Gurshaan Sidhu | Undergraduate Research Intern (external) (2018) |
Vanesa Tomas Bosch, MSc | Senior Research Assistant (2018) |
Heather Galley, BSc (Hons) | Research Assistant (2018) |
Helen Do | Undergraduate Research Intern (2018) |
Lea Sanchez Milde, BSc | Lab Assistant (part-time) (2018) |
Michelle Chan YeeTeng | Undergraduate Research Intern (2018) |
Quratulain Qureshi | Undergraduate Research Intern (2018) |
Naiomi Lu, BSc |
Undergraduate Research Intern (2017)
VPR Undergraduate Student Research Award (USRA) Recipient (2017) Lab Assistant (2017-2018) |
Sreedevi Kesavan | Undergraduate Research Intern (2017) |
Daniella Bavaro | Undergraduate Research Intern (2017) |
Saru Sandhu | Undergraduate Research Intern (2017) |
Shianne Bains | Undergraduate Research Intern (2017) |
Alekhya Josyula, BSc | MSc student (2014-2017) |
Vivian Qian Liu, PhD | Postdoctoral Fellow (2016) |
Iva Demirova |
Grade 11 Pre-International Baccalaureate (IB) Research Intern (2015-2016)
National Sanofi Biogenius Award Student (2016) |
Nina Maglanoc | Undergraduate Research Intern (2015-2016) |
Ruth Wijaya |
Undergraduate Research Intern (2014-2016)
Undergraduate Research Award (USRA) Student (2015) |
Jessica Parker | Undergraduate Research Intern (2015) |
Alexandra Vela | Research Intern (2015) |
Caitlin Rempel |
Undergraduate Research Intern (2013-2014)
Research Assistant & Acting Lab Manager (2014) |
Timothy Crowe | MSc Student (2013-2014) |
Megan Curpen | Research Intern (2013-2014) |
Natalia Savasteeva | Visiting Student (Concordia U) Research Intern (2014) |
Simrita Sandhu | Research Intern (2014) |
Barinder Sangha | Honors Student (2014) |
Natalie Kinloch | Research Intern (2014) |
Dennis Chau |
Research Assistant & Acting Lab Manager (2013-2014)
Research Intern (2010-2011; 2012-2013) |
Angela Trinh | Research Intern (2013) |
Sophia Tsai | Research Intern (2013) |
Kate Auyeung, BSc |
Senior Research Assistant (2009-2013)
Lab Manager (2011-2013) |
Allan Linde | Research Intern (2012) |
Jessica Sidhu | Research Intern (2012) |
Sunny Tang | Research Intern (2011-2012) |
Savrina Manhas, BSc | MSc Student (2010-2012) |
Fatima Ahmed, BSc | MSc Student (2010-2012) |
Irina Vicol | Honors Student (2012) |
Maxim Parfyonov | Research Intern (2012) |
Lauretta Yu | Research Intern (2011) |
Lisa Kieneker | Honors Student (2011) |
Ben Chan | Undergraduate Research Assistant (2011) |
Matt Michaleski |
Honors Student (2010)
Lab Assistant (2010-2011) |
Brenda Clark, MSc |
Senior Research Assistant (2009-2011)
Lab Manager (2009-2011) |
Basim Nehal | Research Intern (2011) |
Jose-Tam Huang | Research Intern (2010-2011) |
James Kwon | Research Intern (2010-2011) |
Sima Gerami | Research Intern (2010) |
Abby Lin | Research Intern (2010) |