New publication: A TLR-4 adjuvanted glycoside analog of mammalian oligomannose evokes HIV-1 cross-reactive antibodies

Further steps to understanding conditions for eliciting HIV-neutralizing antibodies with specificity for oligomannose published in @Scientific Reports [article] and highlighted in SFU’s Scholarly Impact of the Week [PDF]

Diana presents her research on flu antibodies at SFU’s Undergraduate Research Symposium

Diana, an Undergraduate Student Research Award (USRA) recipient in the Pantophlet Lab, presented results from her exciting project on the apparent binding preference of broadly neutralizing antibody precursors to flu hemagglutinin at the remotely held 2021 SFU Undergrad Research Symposium. Diana was recently accepted into the Immunology PhD program at the University of Toronto – we wish her the best as she embarks on the next chapter in her academic career!

Towards a Universal Flu Vaccine (PDF)

Undergraduate Research Symposium 2021 – Diana Yang (video)

 

Ralph receives the 2021 CAHR-CANFAR Excellence in Research Award for HIV Research

Ralph Pantophlet has won the 2021 CAHR-CANFAR Excellence in Research Award in the Basic Science category. This recognition, awarded by the Canadian Association for HIV Research (CAHR) and the Canadian Foundation for AIDS Research (CANFAR),  is “intended to highlight and celebrate the contributions of Canadian researchers in HIV/AIDS research in Canada and internationally”. The award was bestowed at the 30th CAHR conference in May 2021, which was held remotely due to COVID-19.

New funding for equipment in support of COVID-19 research

Welcome Hajar Chihab – New postdoctoral fellow in the Pantophlet Lab

A warm welcome to Hajar Chihab, the Pantophlet’s Lab’s newest postdoc. Hajar obtained her PhD in Immunovirology from the Chouaib Doukkali University in El Jadida, Morocco, under the primary supervision of Dr. Soumaya Benjelloun. Her doctoral research encompassed many aspects of host-virus interaction in the context of hepatitis B and C infections, from the study of viral genome mutations or variations and their influence on the persistence and clearance of viral infection to the study of hepatitis B and C host biomarkers involved in immune responses.

Yiqiu and Diana receive FHS Dean’s USRA!

Congratulations to two talented undergrad students in the Pantophlet Lab: Yiqiu Yang and Diana Yang! Both received news recently of their successful Undergraduate Student Research Award (USRA) applications to the Faculty of Health Sciences (FHS). The awards will support them financially as they contribute to ongoing research projects in the lab this Fall (2020). Yiqiu, who has been a member of the lab since 2019, will continue to work on neutralizing antibodies to the high-mannose patch on HIV gp120. Diana, a new recruit to the lab, will contribute to research on the selective recognition of flu hemagglutinin by germline precursors of broadly neutralizing antibodies.

Interview with Vancouver’s The Tyee on antibody-based therapy for COVID-19

Vancouver biotech company AbCellera is developing antibodies to treat COVID-19. In the six-minute video below from The Tyee, Ralph Pantophlet is interviewed alongside Véronique Lecault, COO of AbCellera. They explain what antibody treatment is and endeavors to apply it to COVID-19. The video also explains how advances in technology are helping to find and isolate the right antibodies.

 

Serum alpha-mannosidase as an additional barrier to eliciting oligomannose-specific HIV-1-neutralizing antibodies

Our latest research contribution to identifying potential hurdles to the elicitation of glycan-specific HIV-neutralizing antibodies has just been published with @SpringerNature in @Scientific Reports! Read here: [article]

Meet SFU undergraduate researcher Yiqiu Yang

Yiqiu, one of our talented undergrad research interns and a 3rd year student in the Department of Molecular Biology and Biochemistry, talks to SFU-SURJ (Science Undergraduate Research Journal) about the research that she has contributed to in the lab over the last several months.

[article]

Quiana receives USRA and admittance to the graduate program in Health Sciences!

Congratulations to Quiana Ang! Quiana has been awarded her second Undergraduate Student Research Award (USRA), which will enable her to continue her undergraduate research in the Pantophlet Lab over the summer, and has been accepted as a Master’s student in the Faculty of Health Sciences for Fall 2020!