Pantophlet Lab part of $140M government funding commitment to equip Canada for future health emergencies and enhance capacity

On May 6, 2024, the Government of Canada announced a $140 million investment to support Canada’s Immuno-Engineering and Biomanufacturing Hub (CIEBH). Led by the University of British Columbia, this initiative includes over 50 partners from academia, industry, non-profits, and the health sector.

This funding will drive four crucial projects to speed up the development and production of life-saving medicines for British Columbia and Canada. These initiatives aim to help Canada respond quickly to future pandemic threats and address significant health challenges.

The CIEBH projects are part of a broader strategy by the Government of Canada to strengthen the domestic biomanufacturing and life sciences sector. This effort ensures the country is ready for future health emergencies.

The Pantophlet Lab is thrilled to be part of the PROGENITER (Pathogen Response Optimization by GENeratIng ThErapeutics Rationally) project. PROGENITER received $14.46 million in research funds from the Canada Biomedical Research Fund Award and $16.40 million in infrastructure funds from the Biosciences Research Infrastructure Fund Award.

Read the Government of Canada announcement here [PDF]

Read the full CBRF-BRIF results (stage 2) here [PDF]


Quiana wins travel award for CSI 2022

Quiana Ang, a Master’s graduate student in the Pantophlet Lab, has won a coveted Paraza Travel Award ($500) to attend the 34th Annual Canadian Society for Immunology Conference, to be held from June 17 – 20, in Halifax, Nova Scotia. Quiana will be presenting her latest research on the development of human cytomegalovirus (HCMV) spike protein derivatives as vaccine candidates for the elicitation of HCMV-neutralizing antibodies.

2022 CSI Travel Awards (PDF)

New publication: A TLR-4 adjuvanted glycoside analog of mammalian oligomannose evokes HIV-1 cross-reactive antibodies

Further steps to understanding conditions for eliciting HIV-neutralizing antibodies with specificity for oligomannose published in @Scientific Reports [article] and highlighted in SFU’s Scholarly Impact of the Week [PDF]

Diana presents her research on flu antibodies at SFU’s Undergraduate Research Symposium

Diana, an Undergraduate Student Research Award (USRA) recipient in the Pantophlet Lab, presented results from her exciting project on the apparent binding preference of broadly neutralizing antibody precursors to flu hemagglutinin at the remotely held 2021 SFU Undergrad Research Symposium. Diana was recently accepted into the Immunology PhD program at the University of Toronto – we wish her the best as she embarks on the next chapter in her academic career!

Towards a Universal Flu Vaccine (PDF)

Undergraduate Research Symposium 2021 – Diana Yang (video)


Ralph receives the 2021 CAHR-CANFAR Excellence in Research Award for HIV Research

Ralph Pantophlet has won the 2021 CAHR-CANFAR Excellence in Research Award in the Basic Science category. This recognition, awarded by the Canadian Association for HIV Research (CAHR) and the Canadian Foundation for AIDS Research (CANFAR),  is “intended to highlight and celebrate the contributions of Canadian researchers in HIV/AIDS research in Canada and internationally”. The award was bestowed at the 30th CAHR conference in May 2021, which was held remotely due to COVID-19.

New funding for equipment in support of COVID-19 research

Welcome Hajar Chihab – New postdoctoral fellow in the Pantophlet Lab

A warm welcome to Hajar Chihab, the Pantophlet’s Lab’s newest postdoc. Hajar obtained her PhD in Immunovirology from the Chouaib Doukkali University in El Jadida, Morocco, under the primary supervision of Dr. Soumaya Benjelloun. Her doctoral research encompassed many aspects of host-virus interaction in the context of hepatitis B and C infections, from the study of viral genome mutations or variations and their influence on the persistence and clearance of viral infection to the study of hepatitis B and C host biomarkers involved in immune responses.

Yiqiu and Diana receive FHS Dean’s USRA!

Congratulations to two talented undergrad students in the Pantophlet Lab: Yiqiu Yang and Diana Yang! Both received news recently of their successful Undergraduate Student Research Award (USRA) applications to the Faculty of Health Sciences (FHS). The awards will support them financially as they contribute to ongoing research projects in the lab this Fall (2020). Yiqiu, who has been a member of the lab since 2019, will continue to work on neutralizing antibodies to the high-mannose patch on HIV gp120. Diana, a new recruit to the lab, will contribute to research on the selective recognition of flu hemagglutinin by germline precursors of broadly neutralizing antibodies.